5,285 research outputs found

    Resonant Dimer Relaxation in Cold Atoms with a Large Scattering Length

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    Efimov physics refers to universal phenomena associated with a discrete scaling symmetry in the 3-body problem with a large scattering length. The first experimental evidence for Efimov physics was the recent observation of a resonant peak in the 3-body recombination rate for 133Cs atoms with large negative scattering length. There can also be resonant peaks in the atom-dimer relaxation rate for large positive scattering length. We calculate the atom-dimer relaxation rate as a function of temperature and show how measurements of the relaxation rate can be used to determine accurately the parameters that govern Efimov physics.Comment: 4 pages, 2 eps figures, normalization error in figures corrected, equations unchange

    Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3

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    Spinocerebellar ataxia type 3 (SCA3), also known as Machado-Joseph disease (MJD), is an autosomal-dominant neurodegenerative disorder caused by a polyglutamine expansion in ataxin-3 (SCA3, MJD1) protein. In biochemical experiments we demonstrate that mutant SCA3exp specifically associated with the type 1 inositol 1,4,5-trisphosphate receptor (InsP3R1), an intracellular calcium (Ca2+) release channel. In electrophysiological and Ca2+ imaging experiments we show that InsP3R1 are sensitized to activation by InsP3 in the presence of mutant SCA3exp. We found that feeding SCA3-YAC-84Q transgenic mice with dantrolene, a clinically relevant stabilizer of intracellular Ca2+ signaling, improved their motor performance and prevented neuronal cells loss in pontine nuclei and substantia nigra regions. Our results indicate that deranged Ca2+ signaling may play an important role in SCA3 pathology and that Ca2+ signaling stabilizers such as dantrolene may be considered as potential therapeutic drugs for treatment of SCA3 patients

    Tracking the Amide I and αCOO− Terminal ν(C=O) Raman Bands in a Family of L-Glutamic Acid-Containing Peptide Fragments: A Raman and DFT Study

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    The E-hook of β-tubulin plays instrumental roles in cytoskeletal regulation and function. The last six C-terminal residues of the βII isotype, a peptide of amino acid sequence EGEDEA, extend from the microtubule surface and have eluded characterization with classic X-ray crystallographic techniques. The band position of the characteristic amide I vibration of small peptide fragments is heavily dependent on the length of the peptide chain, the extent of intramolecular hydrogen bonding, and the overall polarity of the fragment. The dependence of the E residue’s amide I ν(C=O) and the αCOO− terminal ν(C=O) bands on the neighboring side chain, the length of the peptide fragment, and the extent of intramolecular hydrogen bonding in the structure are investigated here via the EGEDEA peptide. The hexapeptide is broken down into fragments increasing in size from dipeptides to hexapeptides, including EG, ED, EA, EGE, EDE, DEA, EGED, EDEA, EGEDE, GEDEA, and, finally, EGEDEA, which are investigated with experimental Raman spectroscopy and density functional theory (DFT) computations to model the zwitterionic crystalline solids (in vacuo). The molecular geometries and Boltzmann sum of the simulated Raman spectra for a set of energetic minima corresponding to each peptide fragment are computed with full geometry optimizations and corresponding harmonic vibrational frequency computations at the B3LYP/6-311++G(2df,2pd) level of theory. In absence of the crystal structure, geometry sampling is performed to approximate solid phase behavior. Natural bond order (NBO) analyses are performed on each energetic minimum to quantify the magnitude of the intramolecular hydrogen bonds. The extent of the intramolecular charge transfer is dependent on the overall polarity of the fragment considered, with larger and more polar fragments exhibiting the greatest extent of intramolecular charge transfer. A steady blue shift arises when considering the amide I band position moving linearly from ED to EDE to EDEA to GEDEA and, finally, to EGEDEA. However, little variation is observed in the αCOO− ν(C=O) band position in this family of fragments

    IMAGES I. Strong evolution of galaxy kinematics since z=1

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    (abbreviated) We present the first results of the ESO large program, ``IMAGES'' which aims at obtaining robust measurements of the kinematics of distant galaxies using the multi-IFU mode of GIRAFFE on the VLT. 3D spectroscopy is essential to robustly measure the often distorted kinematics of distant galaxies (e.g., Flores et al. 2006). We derive the velocity fields and σ\sigma-maps of 36 galaxies at 0.4<z<0.75 from the kinematics of the [OII] emission line doublet, and generate a robust technique to identify the nature of the velocity fields based on the pixels of the highest signal-to-noise ratios (S/N). We have gathered a unique sample of 63 velocity fields of emission line galaxies (W0([OII]) > 15 A) at z=0.4-0.75, which are a representative subsample of the population of M_stellar>1.5x10^{10} M_sun emission line galaxies in this redshift range, and are largely unaffected by cosmic variance. Taking into account all galaxies -with or without emission lines- in that redshift range, we find that at least 41+/-7% of them have anomalous kinematics, i.e., they are not dynamically relaxed. This includes 26+/-7% of distant galaxies with complex kinematics, i.e., they are not simply pressure or rotationally supported. Our result implies that galaxy kinematics are among the most rapidly evolving properties, because locally, only a few percent of the galaxies in this mass range have complex kinematics.Comment: 17 pages, 6 figures, Accepted by A&

    Relaxation and reconstruction on (111) surfaces of Au, Pt, and Cu

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    We have theoretically studied the stability and reconstruction of (111) surfaces of Au, Pt, and Cu. We have calculated the surface energy, surface stress, interatomic force constants, and other relevant quantities by ab initio electronic structure calculations using the density functional theory (DFT), in a slab geometry with periodic boundary conditions. We have estimated the stability towards a quasi-one-dimensional reconstruction by using the calculated quantities as parameters in a one-dimensional Frenkel-Kontorova model. On all surfaces we have found an intrinsic tensile stress. This stress is large enough on Au and Pt surfaces to lead to a reconstruction in which a denser surface layer is formed, in agreement with experiment. The experimentally observed differences between the dense reconstruction pattern on Au(111) and a sparse structure of stripes on Pt(111) are attributed to the details of the interaction potential between the first layer of atoms and the substrate.Comment: 8 pages, 3 figures, submitted to Physical Review

    IMAGES-III: The evolution of the Near-Infrared Tully-Fisher relation over the last 6 Gyr

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    Using the multi-integral field spectrograph GIRAFFE at VLT, we have derived the K-band Tully-Fisher relation (TFR) at z~0.6 for a representative sample of 65 galaxies with emission lines. We confirm that the scatter in the z~0.6 TFR is caused by galaxies with anomalous kinematics, and find a positive and strong correlation between the complexity of the kinematics and the scatter that they contribute to the TFR. Considering only relaxed-rotating disks, the scatter, and possibly also the slope of the TFR, do not appear to evolve with z. We detect an evolution of the K-band TFR zero point between z~0.6 and z=0, which, if interpreted as an evolution of the K-band luminosity of rotating disks, would imply that a brightening of 0.66+/-0.14 mag occurs between z~0.6 and z=0. Any disagreement with the results of Flores et al. (2006) are attributed to both an improvement of the local TFR and the more detailed accurate measurement of the rotation velocities in the distant sample. Most of the uncertainty can be explained by the relatively coarse spatial-resolution of the kinematical data. Because most rotating disks at z~0.6 are unlikely to experience further merging events, one may assume that their rotational velocity does not evolve dramatically. If true, our result implies that rotating disks observed at z~0.6 are rapidly transforming their gas into stars, to be able to double their stellar masses and be observed on the TFR at z=0. The rotating disks observed are indeed emission-line galaxies that are either starbursts or LIRGs, which implies that they are forming stars at a high rate. Thus, a significant fraction of the rotating disks are forming the bulk of their stars within 6 to 8 Gyr, in good agreement with former studies of the evolution of the M-Z relation.Comment: 17 pages, 11 figures, accepted for publication in A&A. v2 taking into account comments from language edito

    Caltech Faint Galaxy Redshift Survey X: A Redshift Survey in the Region of the Hubble Deep Field North

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    A redshift survey has been carried out in the region of the Hubble Deep Field North using the Low Resolution Imaging Spectrograph at the Keck Observatory. The resulting redshift catalog, which contains 671 entries, is a compendium of our own data together with published LRIS/Keck data. It is more than 92% complete for objects, irrespective of morphology, to R=24R = 24 mag in the HDF itself and to R=23R = 23 mag in the Flanking Fields within a diameter of 8 arcmin centered on the HDF, an unusually high completion for a magnitude limited survey performed with a large telescope. A median redshift z=1.0z = 1.0 is reached at R23.8R \sim 23.8. Strong peaks in the redshift distribution, which arise when a group or poor cluster of galaxies intersect the area surveyed, can be identified to z1.2z \sim 1.2 in this dataset. More than 68% of the galaxies are members of these redshift peaks. In a few cases, closely spaced peaks in zz can be resolved into separate groups of galaxies that can be distinguished in both velocity and location on the sky. The radial separation of these peaks in the pencil-beam survey is consistent with a characteristic length scale for the their separation of \approx70 Mpc in our adopted cosmology (h=0.6,ΩM=0.3h = 0.6, \Omega_M = 0.3, Λ=0\Lambda = 0). Strong galaxy clustering is in evidence at all epochs back to z1.1z \le 1.1. (abstract abridged)Comment: Accepted to the ApJ. This version contains all the figures and tables. 2 minor typos in table 2b correcte

    Barred Galaxies in the Coma Cluster

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    We use ACS data from the HST Treasury survey of the Coma cluster (z~0.02) to study the properties of barred galaxies in the Coma core, the densest environment in the nearby Universe. This study provides a complementary data point for studies of barred galaxies as a function of redshift and environment. From ~470 cluster members brighter than M_I = -11 mag, we select a sample of 46 disk galaxies (S0--Im) based on visual classification. The sample is dominated by S0s for which we find an optical bar fraction of 47+/-11% through ellipse fitting and visual inspection. Among the bars in the core of the Coma cluster, we do not find any very large (a_bar > 2 kpc) bars. Comparison to other studies reveals that while the optical bar fraction for S0s shows only a modest variation across low-to-intermediate density environments (field to intermediate-density clusters), it can be higher by up to a factor of ~2 in the very high-density environment of the rich Coma cluster core.Comment: Proceedings of the Bash symposium, to appear in the Astronomical Society of the Pacific Conference Series, eds. L. Stanford, L. Hao, Y. Mao, J. Gree

    Measurements of scattering observables for the pdpd break-up reaction

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    High-precision measurements of the scattering observables such as cross sections and analyzing powers for the proton-deuteron elastic and break-up reactions have been performed at KVI in the last two decades and elsewhere to investigate various aspects of the three-nucleon force (3NF) effects simultaneously. In 2006 an experiment was performed to study these effects in p+d\vec{p}+d break-up reaction at 135 MeV with the detection system, Big Instrument for Nuclear polarization Analysis, BINA. BINA covers almost the entire kinematical phase space of the break-up reaction. The results are interpreted with the help of state-of-the-art Faddeev calculations and are partly presented in this contribution.Comment: Proceedings of 19th International IUPAP Conference on Few-Body Problems in Physics, Bonn University, 31.08 - 05.09.2009, Bonn, GERMAN

    Images IV: Strong evolution of the oxygen abundance in gaseous phases of intermediate mass galaxies since z=0.8

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    Intermediate mass galaxies (logM(Msun)>10) at z~0.6 are the likeliest progenitors of the present-day numerous population of spirals. There is growing evidence that they have evolved rapidly since the last 6 to 8 Gyr ago, and likely have formed a significant fraction of their stellar mass, often showing perturbed morphologies and kinematics. We have gathered a representative sample of 88 such galaxies and have provided robust estimates of their gas phase metallicity. For doing so, we have used moderate spectral resolution spectroscopy at VLT/FORS2 with unprecedented high S/N allowing to remove biases coming from interstellar absorption lines and extinction to establish robust values of R23=([OII]3727 + [OIII]4959,5007)/Hbeta. We definitively confirm that the predominant population of z~0.6 starbursts and luminous IR galaxies (LIRGs) are on average, two times less metal rich than the local galaxies at a given stellar mass. We do find that the metal abundance of the gaseous phase of galaxies is evolving linearly with time, from z=1 to z=0 and after comparing with other studies, from z=3 to z=0. Combining our results with the reported evolution of the Tully Fisher relation, we do find that such an evolution requires that ~30% of the stellar mass of local galaxies have been formed through an external supply of gas, thus excluding the close box model. Distant starbursts & LIRGs have properties (metal abundance, star formation efficiency & morphologies) similar to those of local LIRGs. Their underlying physics is likely dominated by gas infall probably through merging or interactions. Our study further supports the rapid evolution of z~0.4-1 galaxies. Gas exchanges between galaxies is likely the main cause of this evolution.Comment: 21 pages, 12 figures, A&A, In pres
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